Nightlife: Main Street, Santa Monica.

No. Really.

If you say nothing happens on Main Street in Santa Monica, nobody's going to argue with you, but it's not really true. The World Cafe has returned to its roots midweek evenings in the no-cover front lounge, with "Hump Day Comedy" stand-up Wednesdays at 9 and live acoustic music Tuesdays at (I think) 8 (I chanced on a terrific singer-songwriter there a couple of weeks ago). Meanwhile, starting in May, Enterprise Fish Co. introduces "The Lounge," with live DJs, wine and cocktails, and tapas that, if up to the FishCo's usual standards, will be terrific.

In the shorter run, at Powerhouse Theater on Fridays and Saturdays at 8 p.m. and Sundays at 4 p.m. until May 10, Hal Ackerman takes a frank look at his own mortality in his "poignant and often humorous" play, Testosterone: How Prostate Cancer Made a Man of Me, joined by supporting cast members Dennis Lee Kelly and Lisa Robins. Co-chair of the screenwriting program at the U.C.L.A. School of Theater, Film and Television where he has been on the faculty for 22 years, Ackerman completed treatment for prostrate cancer in 2001.

Powerhouse Theater, 3116 2nd, 310-396-3680.
Enterprise Fish Co., 174 Kinney, 310-392-8366.
The World Cafe, 2820 Main, 310-392-1661; carldegreg@yahoo.com